Square media bottles are frequently used in autoclaving processes. This is because, in order to save space and time, it is frequently necessary to load as many bottles as possible into the autoclave. Because many components of the procedure are time sensitive, micro laboratories must process samples fast. They also have to manufacture a lot of media and agar on a regular basis, and they have discovered that racks of square bottles are considerably easier to work with. Solid chemicals in granular form are also routinely stored in square media bottles.

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