Neuropathic pain occurs due to damage or disease directly affecting the somatosensory nervous system. It often manifests as sensations such as burning, stabbing pain, or pins and needles, and can be difficult to treat effectively. Neuropathic pain can occur as a result of diabetes, shingles, surgery, spinal cord injury, cancer, alcoholism, and HIV/AIDS. The rising incidence of nerve debilitating diseases and injuries are key factors driving the demand for neuropathic pain therapeutics.

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