Glucagon like peptide-1 (GLP-1) is an incretin hormone released after eating from L cells mainly located in the intestines. Incretins are hormones released from the gastrointestinal tract that stimulate release of insulin from the pancreas in response to meals. GLP-1 acts as the major incretin in the body and plays an important role in regulating blood glucose levels after eating. When food is consumed, GLP-1 is released which triggers the pancreas to secrete insulin which helps transport glucose from the bloodstream into body cells where it can be used for energy. At the same time, GLP-1 suppresses secretion of glucagon which prevents the liver from releasing excess glucose into the bloodstream. This dual action of stimulating insulin secretion and suppressing glucagon levels is crucial for maintaining normal blood sugar control.


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